{"id":3697193,"date":"2026-04-30T19:18:09","date_gmt":"2026-04-30T23:18:09","guid":{"rendered":"https:\/\/www.pymnts.com\/?p=3697193"},"modified":"2026-04-30T19:18:09","modified_gmt":"2026-04-30T23:18:09","slug":"cancer-never-saw-the-algorithm-coming","status":"publish","type":"post","link":"https:\/\/www.pymnts.com\/artificial-intelligence-2\/2026\/cancer-never-saw-the-algorithm-coming\/","title":{"rendered":"Cancer Never Saw the Algorithm Coming"},"content":{"rendered":"<p>Pancreatic cancer kills most of its patients because there is nothing to find by the time they feel sick. Colorectal cancer kills roughly 53,000 Americans a year for the same reason.<\/p><div\r\n\tid=\"article-paywall-overlay\"\r\n\tclass=\"d-none\"\r\n>\r\n\t<div id=\"article-paywall-content\" class=\"my-4\">\r\n\t\t\n<div class=\"wpcf7 no-js\" id=\"wpcf7-f2699550-o1\" lang=\"en-US\" dir=\"ltr\" data-wpcf7-id=\"2699550\">\n<div class=\"screen-reader-response\"><p role=\"status\" aria-live=\"polite\" aria-atomic=\"true\"><\/p> <ul><\/ul><\/div>\n<form action=\"\/wp-json\/wp\/v2\/posts\/3697193#wpcf7-f2699550-o1\" method=\"post\" class=\"wpcf7-form init pymnts-article-paywall-form\" aria-label=\"Contact form\" novalidate=\"novalidate\" data-status=\"init\">\n<fieldset class=\"hidden-fields-container\"><input type=\"hidden\" name=\"_wpcf7\" value=\"2699550\" \/><input type=\"hidden\" name=\"_wpcf7_version\" value=\"6.1.5\" \/><input type=\"hidden\" name=\"_wpcf7_locale\" value=\"en_US\" \/><input type=\"hidden\" name=\"_wpcf7_unit_tag\" value=\"wpcf7-f2699550-o1\" \/><input type=\"hidden\" 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completing this form, you agree to receive marketing communications from PYMNTS and to the sharing of your information with our sponsor, if applicable, in accordance with our <a class=\"fw-bold\" href=\"https:\/\/pymnts-com-develop.go-vip.net\/privacy-policy\/\">Privacy Policy<\/a> and <a class=\"fw-bold\" href=\"https:\/\/pymnts-com-develop.go-vip.net\/terms-conditions\/\">Terms and Conditions<\/a>.\n\t\t\t\t<\/p>\n\t\t\t\t<p><input id='hiddenPath' type='hidden' name='path' value='' \/><input type='hidden' name='userDeviceId' id='userDeviceId' \/><input type='hidden' name='pageTitle' id='pageTitle' \/>\n\t\t\t\t<\/p>\n\t\t\t<\/div>\n\t\t\t<div class=\"col-12\">\n\t\t\t\t<div id='formButtonRow' class='container mt-1 px-0'>\n\t\t\t\t\t<p><input class=\"wpcf7-form-control wpcf7-submit has-spinner btn btn-dark text-uppercase py-2 px-5 small\" id=\"theSubmitButton\" type=\"submit\" value=\"Submit\" \/>\n\t\t\t\t\t<\/p>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div><input type=\"hidden\" name=\"post_id\" value=\"3697193\" \/><input type=\"hidden\" name=\"source\" value=\"https:\/\/www.pymnts.com\/artificial-intelligence-2\/2026\/cancer-never-saw-the-algorithm-coming\/\" \/><p style=\"display: none !important;\" class=\"akismet-fields-container\" data-prefix=\"_wpcf7_ak_\"><label>&#916;<textarea name=\"_wpcf7_ak_hp_textarea\" cols=\"45\" rows=\"8\" maxlength=\"100\"><\/textarea><\/label><input type=\"hidden\" id=\"ak_js_1\" name=\"_wpcf7_ak_js\" value=\"15\"\/><script>document.getElementById( \"ak_js_1\" ).setAttribute( \"value\", ( new Date() ).getTime() );<\/script><\/p><div class=\"wpcf7-response-output\" aria-hidden=\"true\"><\/div>\n<\/form>\n<\/div>\n\r\n\t<\/div>\r\n<\/div>\r\n<div id=\"article-paywall-hidden-content\">\r\n\t\n<p>The same week that a new philanthropic push pledged $500 million to build artificial intelligence (AI) systems that model disease at the cellular level, two separate research teams published evidence that AI can already see what radiologists cannot.<\/p>\n<h2><strong>Mayo Clinic\u2019s Model Reads a Normal Scan Differently<\/strong><\/h2>\n<p>The numbers behind <a href=\"https:\/\/www.mayoclinic.org\/\">Mayo Clinic<\/a>\u2019s new AI are striking.<\/p>\n<p>A Mayo Clinic-developed model called REDMOD can detect pancreatic cancer on routine abdominal CT scans up to three years before a clinical diagnosis, identifying subtle signs of disease before tumors are visible, when curative treatment may still be possible, Mayo Clinic News Network <a href=\"https:\/\/newsnetwork.mayoclinic.org\/discussion\/mayo-clinic-ai-detects-pancreatic-cancer-up-to-3-years-before-diagnosis-in-landmark-validation-study\/\">reported<\/a> Wednesday (April 29).<\/p>\n<p>Researchers analyzed nearly 2,000 CT scans, including scans from patients later diagnosed with pancreatic cancer that were originally interpreted as normal. REDMOD identified 73% of those prediagnostic cancers at a median of about 16 months before diagnosis, nearly double the detection rate of specialists reviewing the same scans without AI assistance.<\/p>\n<p>The advantage compounded over time. In scans obtained more than two years before diagnosis, the AI identified nearly three times as many early cancers that would otherwise go undetected, Mayo Clinic News Network reported.<\/p><div id=\"pymnt-234474340\" class=\"pymnt-content pymnt-entity-placement\" style=\"margin-top: 50px;\"><p style=\"text-align:center\">Advertisement: Scroll to Continue<\/p><script async type=\"text\/javascript\" id=\"dianomi_context_script\" src=\"https:\/\/www.dianomi.com\/js\/contextfeed.js\"><\/script> \r\n<div class=\"dianomi_context\" data-dianomi-context-id=\"4329\"><\/div><\/div>\n<p>The stakes are real. More than 85% of pancreatic cancer patients receive a diagnosis after the disease has already spread, and five-year survival rates remain below 15%, according to the National Cancer Institute. Projections show pancreatic cancer will become the second-leading cause of cancer-related death in the U.S. by 2030.<\/p>\n<p>REDMOD works by measuring quantitative imaging features that describe tissue texture and structure, capturing faint biological changes before any visible mass forms. The model runs automatically without time-intensive manual preparation and was validated across CT scans from multiple institutions, imaging systems and protocols, Mayo Clinic News Network reported. It is designed to analyze scans already obtained for other reasons, particularly in high-risk patients such as those with new-onset diabetes.<\/p>\n<h2><strong>Alibaba\u2019s Tool Outpaces Radiologists on a Different Cancer<\/strong><\/h2>\n<p>The same week, <a href=\"https:\/\/www.alibaba.com\/\">Alibaba\u2019s<\/a> research arm <a href=\"https:\/\/damo.alibaba.com\/about?language=en\">Damo Academy<\/a> <a href=\"https:\/\/www.scmp.com\/tech\/tech-trends\/article\/3351719\/alibaba-doubles-down-healthcare-ai-new-tool-early-colorectal-cancer-detection\">published<\/a> results for a parallel effort targeting colorectal cancer. Its Coca AI model accurately identified five previously missed cases of colorectal cancer from the non-contrast CT scans of more than 27,000 people, achieving a sensitivity of 86.6% and a specificity of 99.8%.<\/p>\n<p>Damo Academy said Coca outperformed 10 radiologists of varying experience levels by 20.4% on sensitivity, the South China Morning Post reported. The research was developed with Chinese institutions including Guangdong General Hospital and published in the Annals of Oncology. Current diagnostic methods for colorectal cancer, including colonoscopy and CT colonography, are invasive and create discomfort for patients, whereas Coca has the potential to be a non-invasive, cost-effective and scalable tool, according to Damo researchers.<\/p>\n<h2><strong>Biohub Bets $500 Million on the Deeper Problem<\/strong><\/h2>\n<p>The detection breakthroughs matter. But the infrastructure bet announced the same week signals where the field is heading.<\/p>\n<p>The <a href=\"https:\/\/biohub.org\/\">Chan Zuckerberg Biohub<\/a> committed $500 million over five years to AI-driven biology, with $400 million going toward its own work and $100 million aimed at spurring others, <a href=\"https:\/\/www.axios.com\/2026\/04\/29\/zuckerberg-chan-biohub-philanthropy-ai-disease\">Axios reported<\/a> Wednesday. According to the report, Zuckerberg said last year that Biohub\u2019s long-term goal is to cure all human disease through the intersection of AI and biology.<\/p>\n<p>The stated goal is not incremental. Biohub chief <a href=\"https:\/\/www.linkedin.com\/in\/alexrives\/\">Alex Rives<\/a> told Axios that the usefulness of an AI model\u2019s prediction increases exponentially as the scale of the data grows. Most current datasets cover about a billion cells. The aim is to reach an order of magnitude or more beyond that, Rives said.<\/p>\n<p>Biohub is focused on frontier AI and frontier biology, using large-scale models for virtual cells, immune reprogramming and disease prediction, <a href=\"https:\/\/fortune.com\/2026\/02\/01\/chan-zuckerberg-initiative-layoffs-all-in-on-ai-biomedical-research\/\">Fortune reported<\/a>. The ambition sits upstream of what REDMOD and Coca are doing. Scan-reading AI catches disease once the body has already started changing. A virtual cell model, if it works as theorized, could predict which patients will reach that point at all.<\/p>\n<p><em>For all PYMNTS AI coverage, subscribe to the daily <\/em><a href=\"https:\/\/pymnts.com\/subscribe\/\"><em>AI Newsletter<\/em><\/a><em>.<\/em><\/p>\n\r\n<\/div>\r\n<script>\r\n\twindow.pymntsAllowedArticleCount = 2;\r\n\twindow.pymntsPostID = 3697193;\r\n<\/script>","protected":false},"excerpt":{"rendered":"<p>Pancreatic cancer kills most of its patients because there is nothing to find by the time they feel sick. Colorectal cancer kills roughly 53,000 Americans a year for the same reason. Get the Full Story Complete the form to unlock this article and enjoy unlimited free access to all PYMNTS content \u2014 no additional logins [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":3697276,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"content-type":"","inline_featured_image":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[65579],"tags":[9498,150269,3723,9206,133069],"class_list":["post-3697193","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-artificial-intelligence-2","tag-ai","tag-ai-investments","tag-healthcare","tag-news","tag-pymnts-news"],"acf":{"suggested_titles":""},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.2 (Yoast SEO v27.3) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Cancer Never Saw the Algorithm Coming<\/title>\n<meta name=\"description\" content=\"The deadliest cancers hide until it\u2019s too late. 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